01 - Preheat oven to 400°F. Line a baking sheet with parchment paper or lightly grease with cooking spray.
02 - Combine smoked paprika, garlic powder, onion powder, dried thyme, dried oregano, cayenne pepper, salt, and black pepper in a small bowl. Mix thoroughly to blend spices evenly.
03 - Pat salmon fillets completely dry with paper towels. Brush both sides lightly with olive oil. Press the Cajun spice mixture evenly onto the top and sides of each fillet.
04 - Place seasoned salmon fillets on the prepared baking sheet, skin-side down if applicable. Space fillets evenly to ensure proper heat circulation.
05 - Whisk together honey, fresh lemon juice, and melted unsalted butter in a separate small bowl until fully incorporated and smooth.
06 - Spoon half of the honey glaze mixture evenly over the top of each spiced salmon fillet, ensuring good coverage.
07 - Bake for 10 to 12 minutes, or until salmon reaches an internal temperature of 145°F and flakes easily when tested with a fork.
08 - Remove from oven and brush with the remaining honey glaze. Switch oven to broil and return salmon for 1 to 2 minutes until the glaze bubbles and caramelizes. Watch closely to prevent burning.
09 - Transfer salmon to serving plates. Garnish with fresh chopped parsley and accompany with lemon wedges for squeezing over the fish.